Bus Tickets from Des Moines, IA to Milwaukee, WI

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Bus Des Moines to Milwaukee: Trip Overview

Average ticket price$114
Average bus trip duration12h 35m
Number of daily buses3
Earliest bus departure4:20am
Distance306 miles (493 km)
Latest bus departure11:30pm

Des Moines to Milwaukee Bus

Busbud helps you find a bus from Des Moines to Milwaukee. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

We make sure you can find a bus service from Des Moines to Milwaukee from the most reliable bus companies operating this trip.

Whether it is cheap bus tickets or more luxurious buses going to Milwaukee from Des Moines, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions for your trip Des Moines - Milwaukee

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
04/26
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04/27
$98
Today
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04/29
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04/30
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05/01
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busbud logoThe cheapest trip from Des Moines to Milwaukee was searched and found on Apr 27, 2025 with a price of $98

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Des Moines to Milwaukee, as early as possible.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Des Moines and Milwaukee!

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Des Moines to Milwaukee, get comfy and count the stars.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Des Moines to Milwaukee.

Make a music playlist for your bus ride from Des Moines to Milwaukee, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travelers have used their electronic device on board during 2014.

The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

Will you be returning to Des Moines by bus?

Bus from Des Moines to Milwaukee

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